Monday, August 24, 2009

Neuropathy Pain

Neuropathic Pain

What is neuropathic pain? Neuropathy is a medical term (the interruption of the nerves in the peripheral nervous system, especially without encephalopathy and myelopathy, which affects the central nervous system.)

[1] It is generally considered equivalent to a peripheral neuropathy, defined as renal function and structure of the peripheral motor, sensory and autonomic neurons, involving the entire neuron or selected levels

[2] According to some sources, a disorder of cranial nerve neuropathic pain may be seen as

Neuropathic pain is a complex, chronic pain that is usually associated with tissue injury. With myofascial pain, the nerve fibers themselves may be damaged, dysfunctional or injured. These damaged nerve fibers send incorrect signals to other pain centers. The effect of nerve fiber injury includes a change in the function of nerves, both on site of injury and areas around the injury.

What causes neuropathic pain?

Neuropathic pain often seems to have no obvious cause. It responds poorly to standard pain treatment, and could sometimes be worse than better over time. For some people, can cause severe disability. One example of neuropathic pain is called Phantom Limb Syndrome. This occurs when an arm or a leg was removed due to illness or injury, but the brain is still pain messages from the nerves that originally carried impulses from the missing limbs. These nerves now seem misfire and cause myofascial pain. Some common causes of neuropathic pain include: nociceptive and neuropathic pain is caused by different neuron-physiological processes, and therefore tend to respond to different treatments. Neuropathic pain is by receptors on A-delta and C fiber-mediated, as found in skin, bones, connective tissues, and muscles and internal organs. These receptors serve a biologically useful role by locating noxious chemical, thermal and mechanical stimuli. Neuropathic pain can be somatic or visceral in nature. Somatic pain is localized quite well, constant pain described as sharp, gnawing pain, throbbing or. Visceral pain appears, on the other hand, vague in distribution, paroxysmal in nature and is usually described as deep, aching, press and colicky in nature. Examples of neuropathic pain include: post-operative pain, pain associated with trauma and chronic pain of arthritis. Neuropathic myofascial pain usually responds to opioids and no steroidal anti-inflammatory drugs (NSAIDs).

Neuropathic pain is in contrast to nociceptive pain, such as "burning out" "Electric", "tingling" and "shooting" in nature. It may be continuous or paroxysmal in presentation. In the preamble, neuropathic pain by stimulation of peripheral A-delta and C polymodal nociceptors by algogenic substances myofascial pain caused by injuries or pathological changes produced in the peripheral or central nervous systems.

Examples of pathological changes are prolonged peripheral and central neuronal sensitization, central sensitization related damage to nervous system inhibitory functions and abnormal interactions between the somatic and sympathetic nervous system. A feature of neuropathic pain is chronic allodynia and hyperalgesia. Allodynia is pain due to a stimulus that normally is not defined provoke a painful response. Hyperalgesia is defined by an increased sensitivity to normally painful stimuli. Primary hyperalgesia, caused by sensitization of C-fibers, occurs immediately within the framework of the breach. Secondary hyperalgesia, caused by sensitization of dorsal horn neurons that occurs in the undamaged area surrounding the injury


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